GATA Binding Protein 3 (GATA3) Antibody

This gene encodes a protein which belongs to the GATA family of transcription factors.The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology.Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. (provided by RefSeq) Tissue specificity: T-cells and endothelial cells RD: GATA-3 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis.It is widely expressed in mesodermal- and endodermal-derived tissues.GATA-3 has been shown to be an essential regulator for immune cell function, sympathetic neuron development, and the maintenance of the differentiated state in epithelial cells.

Target	GATA Binding Protein 3 (GATA3)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human GATA3 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P23771 (UniProt, ExPASy)
UniProt Secondary AC	Q5VWG7, Q5VWG8, Q96J16
UniProt Entry Name	GATA3_HUMAN
Gene Symbol	GATA3
GeneID	2625
OMIM	131320
HGNC	4172
KEGG	hsa:2625
Ensembl	ENSG00000107485
String	9606.ENSP00000368632
Molecular Weight	48 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on GATA Binding Protein 3 (GATA3)

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