GATA Binding Protein 3 (GATA3) Antibody
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Catalogue No: abx015869
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US$427.75
(Size: 100 µl)
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Datasheet SDS
This gene encodes a protein which belongs to the GATA family of transcription factors.The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology.Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. (provided by RefSeq) Tissue specificity: T-cells and endothelial cells RD: GATA-3 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis.It is widely expressed in mesodermal- and endodermal-derived tissues.GATA-3 has been shown to be an essential regulator for immune cell function, sympathetic neuron development, and the maintenance of the differentiated state in epithelial cells.
Research Articles on GATA Binding Protein 3 (GATA3)
| Target | GATA Binding Protein 3 (GATA3) |
| Research Area | Signal Transduction, Tumor Immunity, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human GATA3 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P23771 (UniProt, ExPASy) |
| UniProt Secondary AC | Q5VWG7, Q5VWG8, Q96J16 |
| UniProt Entry Name | GATA3_HUMAN |
| Gene Symbol | GATA3 |
| GeneID | 2625 |
| OMIM | 131320 |
| HGNC | 4172 |
| KEGG | hsa:2625 |
| Ensembl | ENSG00000107485 |
| String | 9606.ENSP00000368632 |
| Molecular Weight | 48 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |