GATA Binding Protein 4 (GATA4) Antibody
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Catalogue No: abx015870
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
GATA binding protein 4, also known as GATA4, it is a 46 kDa member of the GATA family of zinc-finger transcription factors.Members of this family is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types.These factors recognize the GATA motif which is present in the promoters of many genes.GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain.Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1/2, and weakly through JNK or p38 MAPKs.GATA4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function.Mutations in this gene have been associated with cardiac septal defects.
Research Articles on GATA Binding Protein 4 (GATA4)
| Target | GATA Binding Protein 4 (GATA4) |
| Clonality | Monoclonal |
| Reactivity | Human, Rat |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human GATA4 expressed in E. coli. |
| Isotype | IgG2b |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| GeneID | 2626 |
| Molecular Weight | 46 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |