GATA Binding Protein 4 (GATA4) Antibody

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Catalogue No: abx015870
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
GATA binding protein 4, also known as GATA4, it is a 46 kDa member of the GATA family of zinc-finger transcription factors.Members of this family is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types.These factors recognize the GATA motif which is present in the promoters of many genes.GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain.Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1/2, and weakly through JNK or p38 MAPKs.GATA4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function.Mutations in this gene have been associated with cardiac septal defects.

Target GATA Binding Protein 4 (GATA4)
Clonality Monoclonal
Reactivity Human, Rat
Tested Applications ELISA, WB
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human GATA4 expressed in E. coli.
Isotype IgG2b
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
GeneID 2626
Molecular Weight 46 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on GATA Binding Protein 4 (GATA4)


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