Glycine Amidinotransferase, Mitochondrial (GATM) Antibody
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Catalogue No: abx031173
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
Research Articles on Glycine Amidinotransferase, Mitochondrial (GATM)
| Target | Glycine Amidinotransferase, Mitochondrial (GATM) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human GATM. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P50440 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DH99, B4DPI3, Q53EQ4 |
| UniProt Entry Name | GATM_HUMAN |
| KEGG | hsa:2628 |
| String | 9606.ENSP00000379895 |
| Molecular Weight | Calculated MW: 48.5 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Pig and Monkey GATM. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |