1,4-Alpha-Glucan-Branching Enzyme (GBE1) Antibody

GBE1 is a glycogen branching enzyme that catalyzes the transfer of alpha-1, 4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1, 6 position on the same or a neighboring glycogen chain. Branching of the chains is essential to increase the solubility of the glycogen molecule and, consequently, in reducing the osmotic pressure within cells. Highest level of this enzyme are found in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (also known as Andersen's disease).

Target	1,4-Alpha-Glucan-Branching Enzyme (GBE1)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 527-556 amino acids from the Central region of human GBE1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q04446 (UniProt, ExPASy)
UniProt Secondary AC	B3KWV3, Q96EN0
UniProt Entry Name	GLGB_HUMAN
KEGG	hsa:2632
String	9606.ENSP00000410833
Molecular Weight	Calculated MW: 80.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 1,4-Alpha-Glucan-Branching Enzyme (GBE1)

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