Glycocalicin (GC) Antibody

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. This antibody is supplied as crude ascites.

Target	Glycocalicin (GC)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	WB: 1/100 - 1/1600. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 337-365 amino acids from the Central region of human GC.
Isotype	IgM
Form	Liquid
Purification	Unpurified crude ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P04062 (UniProt, ExPASy)
UniProt Entry Name	GLCM_HUMAN
KEGG	hsa:2629
String	9606.ENSP00000314508
Molecular Weight	Calculated MW: 59.7 kDa
Buffer	Ascites containing 0.09% sodium azide.
Specificity	Predicted to react with Cow and Pig GBA.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Glycocalicin (GC)

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