Glycine C-Acetyltransferase (GCAT) Antibody

The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. GCAT is the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase.

Target	Glycine C-Acetyltransferase (GCAT)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 155-181 amino acids from the Central region of human GCAT.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O75600 (UniProt, ExPASy)
UniProt Secondary AC	E2QC23, Q6ZWF1, Q96CA9
UniProt Entry Name	KBL_HUMAN
KEGG	hsa:23464
String	9606.ENSP00000371110
Molecular Weight	Calculated MW: 45.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow GCAT.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Glycine C-Acetyltransferase (GCAT)

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