Glucagon (GCG) Antibody
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Catalogue No: abx001034
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US$348.00
(Size: 60 µl)
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Datasheet SDS
GCG Antibody is a Rabbit Polyclonal antibody against GCG. The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Research Articles on Glucagon (GCG)
| Target | Glucagon (GCG) |
| Research Area | Neuroscience, Neuropeptides |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human Pro-glucagon |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P01275 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NN65, Q53TP6 |
| UniProt Entry Name | GLUC_HUMAN |
| Gene Symbol | GCG |
| GeneID | 2641 |
| NCBI Accession | NP_002045.1 |
| KEGG | hsa:2641 |
| String | 9606.ENSP00000387662 |
| Molecular Weight | Calculated MW: 20 kDa Observed MW: 21 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
