Growth Differentiation Factor 15 (GDF15) Antibody

GDF15 Antibody is a Rabbit Polyclonal antibody against GDF15. Bone morphogenetic proteins (e.g., BMP9; MIM 605120) are members of the transforming growth factor-beta (see TGFB1; MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

Target	Growth Differentiation Factor 15 (GDF15)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	WB, IHC, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 49-308 of human GDF15.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q99988 (UniProt, ExPASy)
UniProt Secondary AC	O14629, P78360, Q9BWA0, Q9NRT0
UniProt Entry Name	GDF15_HUMAN
Gene Symbol	GDF15
GeneID	9518
NCBI Accession	NP_004855.2
KEGG	hsa:9518
String	9606.ENSP00000252809
Molecular Weight	Calculated MW: 34 kDa Observed MW: 35 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Growth Differentiation Factor 15 (GDF15)

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