Gem Nuclear Organelle Associated Protein 2 (GEMIN2) Antibody

Catalogue No: abx002220
Price: £120.00
(Size: 20 µl)
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GEMIN2 Antibody is a Rabbit Polyclonal antibody against GEMIN2. This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.

Target GEMIN2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human GEMIN2.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O14893 (UniProt, ExPASy)
UniProt Secondary AC B2R9W8, Q2M3B3, Q9H4F5, Q9NS77, Q9NS78, Q9NS79
UniProt Entry Name GEMI2_HUMAN
Gene Symbol GEMIN2
GeneID 8487
KEGG hsa:8487
String 9606.ENSP00000308533
Molecular Weight Calculated MW: 4 kDa, 28 kDa, 29 kDa, 31 kDa
Observed MW: 35 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on GEMIN2

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