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Glial Fibrillary Acidic Protein (GFAP) Antibody
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Catalogue No: abx025232
Price:
US$326.25
(Size: 80 µl)
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This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Research Articles on Glial Fibrillary Acidic Protein (GFAP)
| Target | Glial Fibrillary Acidic Protein (GFAP) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/1000 - 1/2000, IF/ICC: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Human GFAP recombinant protein. |
| Isotype | IgG2b Kappa |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P14136 (UniProt, ExPASy) |
| UniProt Entry Name | GFAP_HUMAN |
| KEGG | hsa:2670 |
| String | 9606.ENSP00000468500 |
| Molecular Weight | Calculated MW: 49.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
