GDNF Family Receptor Alpha 1 (GFRA1) Antibody
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Catalogue No: abx004114
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US$217.50
(Size: 20 µl)
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Datasheet SDS
GFRA1 Antibody is a Rabbit Polyclonal antibody against GFRA1. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.
Research Articles on GDNF Family Receptor Alpha 1 (GFRA1)
| Target | GDNF Family Receptor Alpha 1 (GFRA1) |
| Research Area | Infection Immunity |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to GFRA1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P56159 (UniProt, ExPASy) |
| UniProt Secondary AC | A8KA21, O15507, O43912 |
| UniProt Entry Name | GFRA1_HUMAN |
| Gene Symbol | GFRA1 |
| GeneID | 2674 |
| NCBI Accession | NP_005255.1 |
| KEGG | hsa:2674 |
| String | 9606.ENSP00000347591 |
| Molecular Weight | Calculated MW: 51 kDa Observed MW: 55 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
