Gap Junction Alpha-1 Protein / CX43 (GJA1) Antibody

Gap Junction Alpha-1 Protein / CX43 (GJA1) Antibody is a Rabbit Polyclonal antibody against GJA1. This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.

Target	Gap Junction Alpha-1 Protein / CX43 (GJA1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 283-382 of human Connexin 43.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P17302 (UniProt, ExPASy)
UniProt Secondary AC	B2R5U9, Q6FHU1, Q9Y5I8
UniProt Entry Name	CXA1_HUMAN
Gene Symbol	GJA1
GeneID	2697
NCBI Accession	NP_000156.1
KEGG	hsa:2697
String	9606.ENSP00000282561
Molecular Weight	Calculated MW: 43 kDa Observed MW: 43 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Gap Junction Alpha-1 Protein / CX43 (GJA1)

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