Globotriaosylceramide (CD77) Antibody (FITC)

Globotriaosylceramide (CD77) Antibody (FITC) is a rat monoclonal antibody against Globotriaosylceramide (CD77). The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. This protein, a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor. Alternatively spliced transcript variants have been found for this gene.

Target	Globotriaosylceramide (CD77)
Clonality	Monoclonal
Clone	N884
Reactivity	Human
Tested Applications	FCM
Host	Rat
Recommended dilutions	FCM: 4 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	FITC
Immunogen	Daudi cell line (Burkitt's lymphoma).
Isotype	Rat IgM
Form	Liquid
Purification	The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Storage	Store in the dark at 2°C to 8°C. Avoid exposure to light. Do not freeze.
Shelf Life	The shelf life is at least 24 months.
Buffer	Stabilizing TBS solution with 15 mM sodium azide.
Specificity	The rat monoclonal antibody recognizes CD77 (globotriaosylceramide Gb3), a neutral glycosphingolipid expressed mainly on the surface of B cell populations, such as germinal center B cells and Burkitt's lymphoma cells.
Availability	Shipped within 5-12 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Globotriaosylceramide (CD77)

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