Glutaminase (GLS) Antibody

GLS Antibody is a Rabbit Polyclonal antibody against GLS. This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.

Target	Glutaminase (GLS)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 610-669 of human Glutaminase (GLS).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O94925 (UniProt, ExPASy)
UniProt Secondary AC	Q9UL05, Q9UL06, Q9UL07, Q9UN40
UniProt Entry Name	GLSK_HUMAN
Gene Symbol	GLS
GeneID	2744
NCBI Accession	NP_055720.3
KEGG	hsa:2744
String	9606.ENSP00000317379
Molecular Weight	Calculated MW: 73 kDa Observed MW: 65-73 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Glutaminase (GLS)

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