Glutamate Decarboxylase 2 (GAD2) Antibody (Biotin)

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Catalogue No: abx273244
Price: US$435.00
(Size: 200 µl)

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Datasheet SDS
Glutamate Decarboxylase 2 (GAD2) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Glutamate Decarboxylase 2 (GAD2). This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Target Glutamate Decarboxylase 2 (GAD2)
Clonality Polyclonal
Reactivity Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Biotin
Isotype IgG
Form Liquid
Purification Purified by antigen-specific affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q05683 (UniProt, ExPASy)
UniProt Entry Name DCE2_RAT
Gene Symbol GAD2
GeneID 24380
KEGG rno:24380
Ensembl ENSRNOG00000018200
String 10116.ENSRNOP00000024901
Buffer 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability Shipped within 5-15 working days.
Note This product is for research use only.
Research Articles on Glutamate Decarboxylase 2 (GAD2)


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