Glutamate Decarboxylase 2 (GAD2) Antibody
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Catalogue No: abx412422
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US$1,145.50
(Size: 100 µl)
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Datasheet SDS
Glutamate Decarboxylase 2 (GAD2) Antibody is a Rabbit Polyclonal antibody against GLUTAMATE DECARBOXYLASE 1/2. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Research Articles on Glutamate Decarboxylase 2 (GAD2)
| Target | Glutamate Decarboxylase 2 (GAD2) |
| Research Area | Enzymes and Kinases, Endocrinology, Neuroscience, Autoimmunity |
| Clonality | Polyclonal |
| Reactivity | Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | Validated in IHC-F and IHC-P. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified |
| Storage | Aliquot and store at -20°C. Aliquots can be stored at 2-8°C for up to 1 month. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q05683 (UniProt, ExPASy) |
| UniProt Entry Name | DCE2_RAT |
| Gene Symbol | GAD2 |
| GeneID | 24380 |
| KEGG | rno:24380 |
| Ensembl | ENSRNOG00000018200 |
| String | 10116.ENSRNOP00000024901 |
| Buffer | PBS. Contains sodium azide. |
| Specificity | Recognises both molecular forms of glutamate decarboxylase, GAD1 (67 kDa) and GAD2 (65 kDa). |
| Availability | Shipped within 3-7 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |