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Glutathione Peroxidase 1 (GPX1) Antibody

Catalogue No: abx001027
Price: £120.00
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GPX1 Antibody is a Rabbit Polyclonal antibody against GPX1. This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Target GPX1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human GPX1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P07203 (UniProt, ExPASy)
UniProt Secondary AC E9PAS1, Q7Z5H1, Q9BW12
UniProt Entry Name GPX1_HUMAN
Gene Symbol GPX1
GeneID 2876
KEGG hsa:287
String 9606.ENSP00000407375
Molecular Weight Calculated MW: 10 kDa, 22 kDa
Observed MW: 22 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Glutathione Peroxidase 1 (GPX1) Antibody

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