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Glutathione Peroxidase 1 (GPX1) Antibody
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Catalogue No: abx001027
Price:
US$348.00
(Size: 60 µl)
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GPX1 Antibody is a Rabbit Polyclonal antibody against GPX1. This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Research Articles on Glutathione Peroxidase 1 (GPX1)
| Target | Glutathione Peroxidase 1 (GPX1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human GPX1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P07203 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PAS1, Q7Z5H1, Q9BW12 |
| UniProt Entry Name | GPX1_HUMAN |
| Gene Symbol | GPX1 |
| GeneID | 2876 |
| NCBI Accession | NP_000572.2 |
| KEGG | hsa:2876 |
| String | 9606.ENSP00000407375 |
| Molecular Weight | Calculated MW: 10 kDa/22 kDa Observed MW: 22 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
