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Glutathione Peroxidase 4 (GPX4) Antibody

Catalogue No: abx001579
Price: £120.00
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Glutathione Peroxidase 4 (GPX4) Antibody Glutathione Peroxidase 4 (GPX4) Antibody Glutathione Peroxidase 4 (GPX4) Antibody

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GPX4 Antibody is a Rabbit Polyclonal antibody against GPX4. Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq, Jul 2008].

Target GPX4
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human GPX4.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P36969 (UniProt, ExPASy)
UniProt Secondary AC O43381, Q6PJ59, Q9UPK2
UniProt Entry Name GPX4_HUMAN
Gene Symbol GPX4
GeneID 2879
KEGG hsa:2879
String 9606.ENSP00000346103
Molecular Weight Calculated MW: 19 kDa, 22 kDa
Observed MW: 25 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Glutathione Peroxidase 4 (GPX4) Antibody

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