Glutathione Peroxidase 4 (GPX4) Antibody

GPX4 Antibody is a Rabbit Polyclonal antibody against GPX4. Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified. [provided by RefSeq, Jul 2008].

Target	Glutathione Peroxidase 4 (GPX4)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/5000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 74-197 of GPX4.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P36969 (UniProt, ExPASy)
UniProt Secondary AC	O43381, Q6PJ59, Q9UPK2
UniProt Entry Name	GPX4_HUMAN
Gene Symbol	GPX4
GeneID	2879
NCBI Accession	NP_002076.2
KEGG	hsa:2879
String	9606.ENSP00000346103
Molecular Weight	Calculated MW: 22 kDa Observed MW: 22 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Glutathione Peroxidase 4 (GPX4)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue