Glutamate Receptor 1 (GRIA1) Antibody

GRIA1 Antibody is a Rabbit Polyclonal antibody against GRIA1. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target	Glutamate Receptor 1 (GRIA1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 330-470 of human GluR1/GRIA1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P42261 (UniProt, ExPASy)
UniProt Secondary AC	B7Z2S0, B7Z2W8, B7Z3F6, B7Z9G9, D3DQI4, E7ESV8, Q2NKM6
UniProt Entry Name	GRIA1_HUMAN
Gene Symbol	GRIA1
GeneID	2890
NCBI Accession	NP_000818.2
KEGG	hsa:2890
String	9606.ENSP00000428994
Molecular Weight	Calculated MW: 102 kDa Observed MW: 100 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	1.01 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Glutamate Receptor 1 (GRIA1)

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