Glutamate Receptor 2 (GRIA2) Antibody
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Catalogue No: abx010851
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US$427.75
(Size: 100 µl)
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Datasheet SDS
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca (2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.
Research Articles on Glutamate Receptor 2 (GRIA2)
| Target | Glutamate Receptor 2 (GRIA2) |
| Research Area | Signal Transduction |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human GRIA2 (AA: 652-807) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified from ascites by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P42262 (UniProt, ExPASy) |
| UniProt Secondary AC | A8MT92, I6L997, Q96FP6 |
| UniProt Entry Name | GRIA2_HUMAN |
| Gene Symbol | GRIA2 |
| GeneID | 2891 |
| OMIM | 138247 |
| HGNC | 4572 |
| KEGG | hsa:2891 |
| Ensembl | ENSG00000120251 |
| String | 9606.ENSP00000296526 |
| Molecular Weight | 98.8 kDa |
| Buffer | PBS, containing 0.05% sodium azide. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |