Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) Antibody

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate) sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

Target	Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 188-217 amino acids from the N-terminal region of human GRIA3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P42263 (UniProt, ExPASy)
UniProt Secondary AC	D3DTF1, Q4VXD5, Q4VXD6, Q9HDA0, Q9HDA1, Q9HDA2, Q9P0H1
UniProt Entry Name	GRIA3_HUMAN
Gene Symbol	GRIA3
KEGG	hsa:2892
String	9606.ENSP00000481554
Molecular Weight	Calculated MW: 101 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat, Monkey and Zebrafish GRIA3.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3)

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