Glutamate Receptor Ionotropic, Kainate 2 (GRIK2) Antibody

GRIK2 Antibody is a Rabbit Polyclonal antibody against GRIK2. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive mental retardation.

Target	Glutamate Receptor Ionotropic, Kainate 2 (GRIK2)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 30-300 of human GRIK2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13002 (UniProt, ExPASy)
UniProt Entry Name	GRIK2_HUMAN
Gene Symbol	GRIK2
GeneID	2898
NCBI Accession	NP_068775.1
KEGG	hsa:2898
String	9606.ENSP00000397026
Molecular Weight	Calculated MW: 103 kDa Observed MW: 115 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Glutamate Receptor Ionotropic, Kainate 2 (GRIK2)

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