Glutamate Receptor Ionotropic, NMDA 2B Phospho-Tyr1474 (GRIN2B pY1474) Antibody

GRIN2B (pY1474) Antibody is a Rabbit Polyclonal antibody against GRIN2B (pY1474). NMDA (NMDA) Receptors are a class of Ionotropic glutamate Receptors. NMDA Receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA Receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This Receptor is the predominant excitatory neurotransmitter Receptor in the mammalian brain.

Target	GRIN2B (pY1474)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around Y1474 of human GRIN2B.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13224 (UniProt, ExPASy)
UniProt Secondary AC	Q12919, Q13220, Q13225, Q14CU4, Q9UM56
UniProt Entry Name	NMDE2_HUMAN
Gene Symbol	GRIN2B
GeneID	2904
NCBI Accession	NP_000825.2
KEGG	hsa:2904
String	9606.ENSP00000477455
Molecular Weight	Calculated MW: 166 kDa Observed MW: 200 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on GRIN2B (pY1474)

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