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GRIN2B (pY1474) Antibody

Catalogue No: abx000405
Price: £230.00
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GRIN2B (pY1474) Antibody GRIN2B (pY1474) Antibody

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GRIN2B (pY1474) Antibody is a Rabbit Polyclonal antibody against GRIN2B (pY1474). N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.

Target GRIN2B (pY1474)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y1474 of human GRIN2B.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13224 (UniProt, ExPASy)
UniProt Secondary AC Q12919, Q13220, Q13225, Q14CU4, Q9UM56
UniProt Entry Name NMDE2_HUMAN
Gene Symbol GRIN2B
GeneID 2904
KEGG hsa:2904
String 9606.ENSP00000477455
Molecular Weight Calculated MW: 166 kDa
Observed MW: 200 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on GRIN2B (pY1474) Antibody

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