Glutamate Metabotropic Receptor 1 (GRM1) Antibody

Catalogue No: abx002156
Price: £120.00
(Size: 20 µl)
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Glutamate Metabotropic Receptor 1 (GRM1) Antibody

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GRM1 Antibody is a Rabbit Polyclonal antibody against GRM1. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Target GRM1
Clonality Polyclonal
Reactivity Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/200 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human GRM1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13255 (UniProt, ExPASy)
UniProt Entry Name GRM1_HUMAN
Gene Symbol GRM1
GeneID 2911
KEGG hsa:2911
String 9606.ENSP00000354896
Molecular Weight Calculated MW: 101 kDa, 132 kDa
Observed MW: 150 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Glutamate Metabotropic Receptor 1 (GRM1) Antibody

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