Growth Factor Receptor Bound Protein 2 (GRB2) Antibody

Growth Factor Receptor Bound Protein 2 (GRB2) Antibody is a Rabbit Polyclonal antibody for the detection of GRB2.

The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target	Growth Factor Receptor Bound Protein 2 (GRB2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	growth factor receptor-bound protein 2
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P62993 (UniProt, ExPASy)
UniProt Secondary AC	P29354, Q14450, Q63057, Q63059
UniProt Entry Name	GRB2_HUMAN
Gene Symbol	GRB2
GeneID	2885
OMIM	108355
HGNC	4566
KEGG	hsa:2885
Ensembl	ENSG00000177885
String	9606.ENSP00000376345
Molecular Weight	Observed MW: 25 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Growth Factor Receptor Bound Protein 2 (GRB2)

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