Glutathione S Transferase Mu 3 (GSTM3) Antibody
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Catalogue No: abx002846
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US$348.00
(Size: 60 µl)
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Datasheet SDS
GSTM3 Antibody is a Rabbit Polyclonal antibody against GSTM3. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.
Research Articles on Glutathione S Transferase Mu 3 (GSTM3)
| Target | Glutathione S Transferase Mu 3 (GSTM3) |
| Research Area | Enzymes and Kinases, Tumor Immunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human GSTM3 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P21266 (UniProt, ExPASy) |
| UniProt Secondary AC | O60550, Q96HA3 |
| UniProt Entry Name | GSTM3_HUMAN |
| Gene Symbol | GSTM3 |
| GeneID | 2947 |
| NCBI Accession | NP_000840.2 |
| KEGG | hsa:2947 |
| String | 9606.ENSP00000256594 |
| Molecular Weight | Calculated MW: 26 kDa Observed MW: 25 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
