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Glutathione S Transferase Mu 3 (GSTM3) Antibody

Catalogue No: abx002846
Price: £120.00
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Glutathione S Transferase Mu 3 (GSTM3) Antibody

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GSTM3 Antibody is a Rabbit Polyclonal antibody against GSTM3. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.

Target GSTM3
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human GSTM3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P21266 (UniProt, ExPASy)
UniProt Secondary AC O60550, Q96HA3
UniProt Entry Name GSTM3_HUMAN
Gene Symbol GSTM3
GeneID 2947
KEGG hsa:2947
String 9606.ENSP00000256594
Molecular Weight Calculated MW: 26 kDa
Observed MW: 27 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Glutathione S Transferase Mu 3 (GSTM3) Antibody

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