Glutathione S-Transferase P (GSTP1) Antibody
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Catalogue No: abx015880
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US$427.75
(Size: 100 µl)
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Datasheet SDS
GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione.GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast.Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.
Research Articles on Glutathione S-Transferase P (GSTP1)
| Target | Glutathione S-Transferase P (GSTP1) |
| Research Area | Cytokines, Tumor Immunity, Infection Immunity, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human GSTP1 expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P09211 (UniProt, ExPASy) |
| UniProt Secondary AC | O00460, Q15690, Q5TZY3 |
| UniProt Entry Name | GSTP1_HUMAN |
| Gene Symbol | GSTP1 |
| GeneID | 2950 |
| OMIM | 134660 |
| HGNC | 4638 |
| KEGG | hsa:2950 |
| Ensembl | ENSG00000084207 |
| String | 9606.ENSP00000381607 |
| Molecular Weight | 23 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |