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Retinal Guanylyl Cyclase 1 (GUCY2D) Antibody

Catalogue No: abx002605
Price: £120.00
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Retinal Guanylyl Cyclase 1 (GUCY2D) Antibody

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GUCY2D Antibody is a Rabbit Polyclonal antibody against GUCY2D. This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases.

Target GUCY2D
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human GUCY2D.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q02846 (UniProt, ExPASy)
UniProt Secondary AC Q6LEA7
UniProt Entry Name GUC2D_HUMAN
Gene Symbol GUCY2D
GeneID 3000
KEGG hsa:3000
String 9606.ENSP00000254854
Molecular Weight Calculated MW: 120 kDa
Observed MW: 95 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Retinal Guanylyl Cyclase 1 (GUCY2D) Antibody

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