Glycophorin C (GYPC) Antibody

GYPC Antibody is a Rabbit Polyclonal antibody against GYPC. Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].

Target	Glycophorin C (GYPC)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human Glycophorin C (GGYPC).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P04921 (UniProt, ExPASy)
UniProt Secondary AC	B2R522, Q53SV9, Q92642
UniProt Entry Name	GLPC_HUMAN
Gene Symbol	GYPC
GeneID	2995
NCBI Accession	NP_002092.1
KEGG	hsa:2995
String	9606.ENSP00000259254
Molecular Weight	Calculated MW: 14 kDa Observed MW: 34 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Glycophorin C (GYPC)

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