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Granzyme B (GZMB) Antibody
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Catalogue No: abx001994
Price:
US$348.00
(Size: 60 µl)
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Datasheet SDS
GZMB Antibody is a Rabbit Polyclonal antibody against GZMB. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
Research Articles on Granzyme B (GZMB)
| Target | Granzyme B (GZMB) |
| Research Area | Apoptosis, Tumor Immunity, Infection Immunity, Immunology, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human GZMB |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P10144 (UniProt, ExPASy) |
| UniProt Secondary AC | Q8N1D2, Q9UCC1 |
| UniProt Entry Name | GRAB_HUMAN |
| Gene Symbol | GZMB |
| GeneID | 3002 |
| OMIM | 123910 |
| NCBI Accession | NP_004122.2 |
| HGNC | 4709 |
| KEGG | hsa:3002 |
| Ensembl | ENSG00000100453 |
| String | 9606.ENSP00000216341 |
| Molecular Weight | Calculated MW: 27 kDa Observed MW: 27 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
