H2A Histone Family, Member Y (H2AFY) Antibody
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Catalogue No: abx005334
Price:
US$232.00
(Size: 20 µl)
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Datasheet SDS
H2AFY Antibody is a Rabbit Polyclonal antibody against H2AFY. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on H2A Histone Family, Member Y (H2AFY)
| Target | H2A Histone Family, Member Y (H2AFY) |
| Research Area | Metabolism |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to H2AFY. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O75367 (UniProt, ExPASy) |
| UniProt Secondary AC | O75377, Q503A8, Q7Z5E3, Q96D41, Q9H8P3, Q9UP96 |
| UniProt Entry Name | H2AY_HUMAN |
| Gene Symbol | H2AFY |
| GeneID | 9555 |
| NCBI Accession | NP_613258.2 |
| KEGG | hsa:9555 |
| String | 9606.ENSP00000423563 |
| Molecular Weight | Calculated MW: 39 kDa Observed MW: 40 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
