H2A Histone Family Member Y2 (H2AFY2) Antibody

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.

Target	H2A Histone Family Member Y2 (H2AFY2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 148-169 amino acids from the Central region of human H2AFY2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9P0M6 (UniProt, ExPASy)
UniProt Secondary AC	Q5SQT2
UniProt Entry Name	H2AW_HUMAN
Gene Symbol	H2AFY2
NCBI Accession	NP_061119.1
String	9606.ENSP00000362352
Molecular Weight	Calculated MW: 40.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on H2A Histone Family Member Y2 (H2AFY2)

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