Histone H2B Type F-S (H2BC12L) Antibody
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Catalogue No: abx030415
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US$326.25
(Size: 80 µl)
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Datasheet SDS
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Research Articles on Histone H2B Type F-S (H2BC12L)
| Target | Histone H2B Type F-S (H2BC12L) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 58-84 amino acids from the Central region of human H2BFS. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P57053 (UniProt, ExPASy) |
| UniProt Secondary AC | A0AVF9, Q5R2W0 |
| UniProt Entry Name | H2BFS_HUMAN |
| Gene Symbol | H2BFS |
| GeneID | 102724334 |
| KEGG | hsa:102724334 |
| String | 9606.ENSP00000481622 |
| Molecular Weight | Calculated MW: 13.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |