Trifunctional Enzyme Subunit Alpha, Mitochondrial (HADHA) Antibody

HADHA Antibody is a Rabbit Polyclonal antibody against HADHA. This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.

Target	Trifunctional Enzyme Subunit Alpha, Mitochondrial (HADHA)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/2000 - 1/6000, IF/ICC: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 484-763 of human HADHA.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P40939 (UniProt, ExPASy)
UniProt Secondary AC	B2R7L4, B4DYP2, Q16679, Q53T69, Q53TA2, Q96GT7, Q9UQC5
UniProt Entry Name	ECHA_HUMAN
Gene Symbol	HADHA
GeneID	3030
NCBI Accession	NP_000173.2
KEGG	hsa:3030
String	9606.ENSP00000370023
Molecular Weight	Calculated MW: 83 kDa Observed MW: 78 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Trifunctional Enzyme Subunit Alpha, Mitochondrial (HADHA)

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