Heart And Neural Crest Derivatives Expressed Protein Protein 2 (HAND2) Antibody

HAND2 Antibody is a Rabbit Polyclonal antibody against HAND2. The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.

Target	Heart And Neural Crest Derivatives Expressed Protein Protein 2 (HAND2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 151-217 of human HAND2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P61296 (UniProt, ExPASy)
UniProt Secondary AC	B6ECG9, O95300, O95301, P97833, Q494T1
UniProt Entry Name	HAND2_HUMAN
Gene Symbol	HAND2
GeneID	9464
NCBI Accession	NP_068808.1
KEGG	hsa:9464
String	9606.ENSP00000352565
Molecular Weight	Calculated MW: 24 kDa Observed MW: 26 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Heart And Neural Crest Derivatives Expressed Protein Protein 2 (HAND2)

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