Hepatitis A Virus Cellular Receptor 2 (HAVCR2) Antibody

HAVCR2 Antibody is a Rabbit Polyclonal antibody against HAVCR2. The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.

Target	Hepatitis A Virus Cellular Receptor 2 (HAVCR2)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 22-202 of human TIM-3/HAVCR2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q8TDQ0 (UniProt, ExPASy)
UniProt Secondary AC	B2RAY2, Q8WW60, Q96K94
UniProt Entry Name	HAVR2_HUMAN
Gene Symbol	HAVCR2
GeneID	84868
NCBI Accession	NP_116171.3
KEGG	hsa:84868
String	9606.ENSP00000312002
Molecular Weight	Calculated MW: 33 kDa Observed MW: 45-70 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Hepatitis A Virus Cellular Receptor 2 (HAVCR2)

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