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Histone Deacetylase 1 (HDAC1) Antibody
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Catalogue No: abx000623
Price:
US$232.00
(Size: 20 µl)
Orders to United States ship from United States
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![Western blot analysis of various lysates using [KD Validated] HDAC1 Antibody at 1/2000 dilution incubated at room temperature for 1.5 hours. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020) Exposure time: 20 s.](https://www.abbexa.com/image/cache/data/products/18B/abx000623_1-500x500.jpg "Histone Deacetylase 1 (HDAC1) Antibody")
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HDAC1 Antibody is a Rabbit Polyclonal antibody against HDAC1. Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Research Articles on Histone Deacetylase 1 (HDAC1)
| Target | Histone Deacetylase 1 (HDAC1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to HDAC1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13547 (UniProt, ExPASy) |
| UniProt Secondary AC | Q92534 |
| UniProt Entry Name | HDAC1_HUMAN |
| Gene Symbol | HDAC1 |
| GeneID | 3065 |
| NCBI Accession | NP_004955.2 |
| KEGG | hsa:3065 |
| String | 9606.ENSP00000362649 |
| Molecular Weight | Calculated MW: 55 kDa Observed MW: 62 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |