Histone Deacetylase 2 (HDAC2) Antibody

This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events.

Target	Histone Deacetylase 2 (HDAC2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 410-439 amino acids from the Central region of human HDAC2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92769 (UniProt, ExPASy)
UniProt Secondary AC	B3KRS5, B4DL58, E1P561, Q5SRI8, Q5SZ86, Q8NEH4
UniProt Entry Name	HDAC2_HUMAN
NCBI Accession	NP_001518.3
KEGG	hsa:3066
String	9606.ENSP00000430432
Molecular Weight	Calculated MW: 55.4 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse and Chicken HDAC2.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone Deacetylase 2 (HDAC2)

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