Histone Deacetylase 3 (HDAC3) Antibody
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Catalogue No: abx015752
Price:
US$427.75
(Size: 100 µl)
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Datasheet SDS
HDAC3: histone deacetylase 3, also known as HD3, RPD3, RPD3-2.Entrez Protein NC_000005.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events.Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family.It has histone deacetylase activity and represses transcription when tethered to a promoter.It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1.This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis.This gene is regarded as a potential tumor suppressor gene.
Research Articles on Histone Deacetylase 3 (HDAC3)
| Target | Histone Deacetylase 3 (HDAC3) |
| Research Area | Enzymes and Kinases |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of HDAC3 (aa224-428) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O15379 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DQE1, O43268, Q9UEI5, Q9UEV0 |
| Gene Symbol | HDAC3 |
| GeneID | 8841 |
| OMIM | 605166 |
| HGNC | 4854 |
| Ensembl | ENSG00000171720 |
| Molecular Weight | 48.8 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |