Histone Deacetylase 4 (HDAC4) Antibody

Catalogue No: abx000624
Price: £120.00
(Size: 20 µl)
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HDAC4 Antibody is a Rabbit Polyclonal antibody against HDAC4. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Target HDAC4
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human HDAC4.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P56524 (UniProt, ExPASy)
UniProt Secondary AC E9PGB9, F5GX36, Q86YH7, Q9UND6
UniProt Entry Name HDAC4_HUMAN
Gene Symbol HDAC4
GeneID 9759
KEGG hsa:9759
String 9606.ENSP00000264606
Molecular Weight Calculated MW: 106 kDa, 119 kDa
Observed MW: 117 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on HDAC4

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