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Histone Deacetylase 4 Phospho-Ser632 (HDAC4 pS632) Antibody
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Catalogue No: abx000407
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US$232.00
(Size: 20 µl)
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Datasheet SDS
HDAC4 (pS632) Antibody is a Rabbit Polyclonal antibody against HDAC4 (pS632). Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Research Articles on Histone Deacetylase 4 Phospho-Ser632 (HDAC4 pS632)
| Target | Histone Deacetylase 4 Phospho-Ser632 (HDAC4 pS632) |
| Clonality | Polyclonal |
| Target Modification | Ser632 |
| Modification | Phosphorylation |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A phospho specific peptide corresponding to residues surrounding S632 of human HDAC4 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P56524 (UniProt, ExPASy) |
| UniProt Secondary AC | E9PGB9, F5GX36, Q86YH7, Q9UND6 |
| UniProt Entry Name | HDAC4_HUMAN |
| Gene Symbol | HDAC4 |
| GeneID | 9759 |
| KEGG | hsa:9759 |
| String | 9606.ENSP00000264606 |
| Molecular Weight | Calculated MW: 119 kDa Observed MW: 140 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |