Histone Deacetylase 6 (HDAC6) Antibody

HDAC6 Antibody is a Rabbit Polyclonal antibody against HDAC6. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Target	Histone Deacetylase 6 (HDAC6)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human HDAC6.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9UBN7 (UniProt, ExPASy)
UniProt Secondary AC	O94975, Q6NT75, Q7L3E5, Q96CY0
Gene Symbol	HDAC6
GeneID	10013
NCBI Accession	NP_006035.2
Molecular Weight	Calculated MW: 131 kDa Observed MW: 160 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone Deacetylase 6 (HDAC6)

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