HDAC8 (pS39) Antibody

HDAC8 (pS39) Antibody is a Rabbit Polyclonal antibody against HDAC8 (pS39). Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	HDAC8 (pS39)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	IF/ICC
Host	Rabbit
Recommended dilutions	IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A phospho specific peptide corresponding to residues surrounding S39 of human HDAC8
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9BY41 (UniProt, ExPASy)
UniProt Entry Name	HDAC8_HUMAN
Gene Symbol	HDAC8
GeneID	55869
String	9606.ENSP00000362674
Molecular Weight	Calculated MW: 42 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on HDAC8 (pS39)

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