Hedgehog Interacting Protein (HHIP) Antibody

HHIP Antibody is a Rabbit Polyclonal antibody against HHIP. This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.[provided by RefSeq, Feb 2011].

Target	Hedgehog Interacting Protein (HHIP)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human HHIP.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q96QV1 (UniProt, ExPASy)
UniProt Secondary AC	Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7
UniProt Entry Name	HHIP_HUMAN
GeneID	64399
NCBI Accession	NP_071920.1
KEGG	hsa:64399
String	9606.ENSP00000296575
Molecular Weight	Calculated MW: 79 kDa Observed MW: 79 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Hedgehog Interacting Protein (HHIP)

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