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Hedgehog Interacting Protein (HHIP) Antibody
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Catalogue No: abx002327
Price:
US$348.00
(Size: 60 µl)
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HHIP Antibody is a Rabbit Polyclonal antibody against HHIP. This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.[provided by RefSeq, Feb 2011].
Research Articles on Hedgehog Interacting Protein (HHIP)
| Target | Hedgehog Interacting Protein (HHIP) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human HHIP |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96QV1 (UniProt, ExPASy) |
| UniProt Secondary AC | Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7 |
| UniProt Entry Name | HHIP_HUMAN |
| GeneID | 64399 |
| NCBI Accession | NP_071920.1 |
| KEGG | hsa:64399 |
| String | 9606.ENSP00000296575 |
| Molecular Weight | Calculated MW: 36 kDa/78 kDa Observed MW: 79 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
