Probable E3 Ubiquitin-Protein Ligase HERC3 (HERC3) Antibody
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Catalogue No: abx031069
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US$326.25
(Size: 80 µl)
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Datasheet SDS
HERC3 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710) like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
Research Articles on Probable E3 Ubiquitin-Protein Ligase HERC3 (HERC3)
| Target | Probable E3 Ubiquitin-Protein Ligase HERC3 (HERC3) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human HERC3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q15034 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K1S5, Q8IXX3 |
| UniProt Entry Name | HERC3_HUMAN |
| KEGG | hsa:8916 |
| String | 9606.ENSP00000385684 |
| Molecular Weight | Calculated MW: 117 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |

