Homocysteine Inducible Endoplasmic Reticulum Stress Inducible Ubiquitin Like Domain Member 1 (HERPUD1) Antibody

The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq].

Target	Homocysteine Inducible Endoplasmic Reticulum Stress Inducible Ubiquitin Like Domain Member 1 (HERPUD1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 55-83 amino acids from the N-terminal region of human HERPUD1.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15011 (UniProt, ExPASy)
UniProt Secondary AC	E9PGD1, O60644, Q6IAN8, Q96D92
UniProt Entry Name	HERP1_HUMAN
KEGG	hsa:9709
String	9606.ENSP00000409555
Molecular Weight	Calculated MW: 43.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Homocysteine Inducible Endoplasmic Reticulum Stress Inducible Ubiquitin Like Domain Member 1 (HERPUD1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue