Heterogeneous Nuclear Ribonucleoprotein A1 (hnRNP A1) Antibody

Heterogeneous Nuclear Ribonucleoprotein A1 (hnRNP A1) Antibody is a Rabbit Polyclonal antibody for the detection of HNRNPA1.

This gene encodes a member of a family of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs), which are RNA-binding proteins that associate with pre-mRNAs in the nucleus and influence pre-mRNA processing, as well as other aspects of mRNA metabolism and transport. The protein encoded by this gene is one of the most abundant core proteins of hnRNP complexes and plays a key role in the regulation of alternative splicing. Mutations in this gene have been observed in individuals with amyotrophic lateral sclerosis 20. Multiple alternatively spliced transcript variants have been found. There are numerous pseudogenes of this gene distributed throughout the genome.

Target	Heterogeneous Nuclear Ribonucleoprotein A1 (hnRNP A1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	heterogeneous nuclear ribonucleoprotein A1
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	P09651 (UniProt, ExPASy)
UniProt Secondary AC	A8K4Z8, Q3MIB7, Q6PJZ7
UniProt Entry Name	ROA1_HUMAN
Gene Symbol	HNRNPA1
GeneID	3178
OMIM	164017
HGNC	5031
KEGG	hsa:3178
Ensembl	ENSG00000135486
String	9606.ENSP00000341826
Molecular Weight	Observed MW: 34 kDa, 38 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	This product is for research use only.

Research Articles on Heterogeneous Nuclear Ribonucleoprotein A1 (hnRNP A1)

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