Hereditary Hemochromatosis Protein (HFE) Antibody

HFE Antibody is a Rabbit Polyclonal antibody against HFE. The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].

Target	Hereditary Hemochromatosis Protein (HFE)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 80-306 of human HFE.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q30201 (UniProt, ExPASy)
UniProt Entry Name	HFE_HUMAN
Gene Symbol	HFE
GeneID	3077
NCBI Accession	NP_000401.1
KEGG	hsa:3077
String	9606.ENSP00000417404
Molecular Weight	Calculated MW: 40 kDa Observed MW: 50 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Hereditary Hemochromatosis Protein (HFE)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue