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Hereditary Hemochromatosis Protein (HFE) Antibody

Catalogue No: abx001186
Price: £120.00
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Hereditary Hemochromatosis Protein (HFE) Antibody

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HFE Antibody is a Rabbit Polyclonal antibody against HFE. The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008].

Target HFE
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human HFE.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q30201 (UniProt, ExPASy)
UniProt Entry Name HFE_HUMAN
Gene Symbol HFE
GeneID 3077
KEGG hsa:307
String 9606.ENSP00000417404
Molecular Weight Calculated MW: 8 kDa, 18 kDa, 27-40 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Hereditary Hemochromatosis Protein (HFE) Antibody

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