Histone Cluster 1, H2ag (HIST1H2AG) Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq].

Target	Histone Cluster 1, H2ag (HIST1H2AG)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 102-130 amino acids from the C-terminal region of human HIST1H2AG.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P0C0S8 (UniProt, ExPASy)
UniProt Secondary AC	P02261, Q2M1R2, Q76PA6
UniProt Entry Name	H2A1_HUMAN
KEGG	hsa:8329 hsa:8330 hsa:8332 hsa:8336 hsa:8969
String	9606.ENSP00000482538
Molecular Weight	Calculated MW: 14.1 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat and Cow H2AC11.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Histone Cluster 1, H2ag (HIST1H2AG)

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