HIST1H3B (pT12) Antibody

HIST1H3B (pT12) Antibody is a Rabbit Polyclonal antibody against HIST1H3B (pT12). Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Target	HIST1H3B (pT12)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic phosphorylated peptide around T11 of human HIST1H3B.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P68431 (UniProt, ExPASy)
UniProt Entry Name	H31_HUMAN
Gene Symbol	H3C1
GeneID	8358
NCBI Accession	NP_003520.1
KEGG	hsa:8350 hsa:8351 hsa:8352 hsa:8353 hsa:8354 hsa:8355 hsa:8356 hsa:8357 hsa:8358 hsa:8968
String	9606.ENSP00000484841
Molecular Weight	Calculated MW: 15 kDa Observed MW: 17 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on HIST1H3B (pT12)

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